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Irreversibility tends to be associated with more than 6 months of therapeutic delay, but its variability is unexplained

In some embodiments, mucoadhesive characteristics are also imparted to otic formulations disclosed herein, by incorporation of mucoadhesive carbomers, such as Carbopol 934P, to the composition (Majithiya et al., AAPS PharmSciTech (2006), 7(3), p

and documentation requirements

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