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Despite this potential for plasticity in adulthood, analyses of DNA methylation in adults have typically focused on stressful or traumatic events occurring during development or have considered DNA methylation in adulthood as a predictor of HPA functioning that confers risk or resilience to subsequent stress exposure 16,17

Lillig et al., 2008

Although no clinical trials have yet evaluated this specific triplet, individual components and dual combinations have shown promising results in R/R AML models ( 4 Opportunities and challenges Although conventional chemotherapy has improved remission rates to some extent, relapse and drug resistance remain major obstacles to successful treatment

Garza, Z