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The FDA is now considering allowing its use in supplements due to its long history of safe use

Artificial bear bile: A novel approach to balancing medical requirements and animal welfare

This method is less commonly used for skin brightening specifically, but is sometimes preferred for ease of administration

Arab J Chem 10:S3310S3317 Rahman MA, Kabir AH, Mandal A, Roy SK, Song Y, Ji HC, Lee KW (2020) Glutathione restores Hg-induced morpho-physiological retardations by inducing phytochelatin and oxidative defense in alfalfa
