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This establishes a prospective link between melatonin as a peripheral circadian zeitgeber (time cue), and the gut ( Peripherally administered exogenous melatonin (sometimes in very high pharmacological doses) can presumably access the various structures involved in local effects even though the non-pineal endogenously synthesized melatonin does not apparently get out

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According to the veterinarian, dialysis would be more beneficial for cats with acute kidney injury (AKI) than cats with CKD, whose kidneys have already been damaged and require steady care
