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[246] screened the Q-Marker of this drug based on the property-response-component ternary relationship

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Use adaptive dosing and staging matched to disease phase and compartment: for example, early ischemiareperfusion may benefit from acute, time-boxed control of mitochondrial bursts and labile iron to limit Fenton chemistry, while chronic vascular or organ remodeling calls for rebalancing NOX activity and ER stress together with lifestyle re-entrainment (exercise, nutrition, sleep, exposure control) to reset redox tone without erasing physiological H 2 O 2 signalling (Poznyak et al

Zhang H, Limphong P, Pieper J, Liu Q, Rodesch CK, Christians E, and Benjamin IJ