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Description

Fitzgerald PJ

Over the past decade, advances in basic medical science have illuminated the structures and functions of key regulators of cholesterol metabolism, including the SCAP-SREBP complex [106], Insig- 1 [107], NPC1/2, ABCA1 [108], ABCG5, and ABCG8 [109]

Landi D, Ragonese P, Prosperini L, Nociti V, Haggiag S, Cortese A, et al

Improved integration with cell isolation techniques and validation in biologically relevant models will be key to translating these technical advances into impactful discoveries, enabling deeper mapping of signalling in primary tissue samples and rare cell populations