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In animal models, both peptides show well-documented effects on healing muscle, tendon, ligament, and gastrointestinal tissues, though they work through distinct biological pathways

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Within the context of the Dihexa pathway, which is studied for its ability to support synaptogenesis through HGF/c-Met signaling, having typical BDNF function suggests that the underlying neuroplasticity pathways that support synapse formation and neural network remodeling likely operate within a normal physiological range