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Description
It operates across multiple signaling networks simultaneously
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Chaudhari SN, Mukherjee M, Vagasi AS, Bi G, Rahman MM, Nguyen CQ, Paul L, Selhub J, Kipreos ET

Origins as a Mitochondrial-Derived Peptide MOTS-C peptide was first characterized in 2015 by Lee and colleagues, who showed that stressed muscle cells release this peptide, which then translocates to the nucleus to upregulate genes involved in adaptive stress resistance