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20 Recently, there has been emerging evidence indicating that abnormal metabolites in the TME play a role in modulating tumoral ferroptosis and immune evasion
Molecules 18, 46894702
Understanding these interactions is important for providers in managing concurrent therapies and minimizing the risk of adverse effects
The initial reaction in this chain is the conversion of citrate (an exporter of mitochondrial acetyl-CoA) to acetyl-CoA by ATP-citrate lyase
