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This results in the activation of mast cells and the release of inflammatory mediators, including histamine, leukotrienes, and others, which can manifest as pruritus, urticaria, angioedema, bronchospasm, vomiting, and hypotension
Burgerstein BIOTICS-G can be stored at room temperature without any problems

The virus usually stays inactive (dormant), but it can reactivate from time to time, often without causing symptoms