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MiRNAs altered upon HI that are central for the regulation of the Wnt/-catenin pathway can also affect the activity of pro-inflammatory MAPK/NF-B, including mir-331-5p downregulated in UCB after HI, mir-2137, and mir-137 upregulated after 24 h in mouse brain exposed to HI (59, 67, 68)

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Additionally, ALA given as a dietary supplement has been shown to be able to reverse age-related decline in kidney function and serum total proteins [140]