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Recent research has revealed that Sarm1-mediated degeneration of catecholaminergic axons in the colon does not exacerbate disease but rather alleviates colitis by disrupting local pro-inflammatory signaling pathways (57)

Both protocols use a before-bed injection and run concurrently without modification to either schedule
We suppose the change is because the initial doses are enough to keep B12 levels within the desired range
