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There are several reports on the role of transition metals in lipid peroxidation process associated with cellular toxicities, because once they enter our physiological systems, these metals play a role in oxidative adverse effects

Although not found consistently across all studies, the following lipid abnormalities have been documented in many studies of individuals with subclinical hypothyroidism: elevated TC, elevated LDL-C, increased TG, and decreased HDL-C [13]

Although there are some of same characteristics as other cell death patterns, parthanatos is a distinct RCD that is characterized by chromatin degradation and particle release into extracellular space