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Nicotine may also act as a stimulant to inhibit the action of the striatal dopamine transporter, increasing dopamine levels in the synaptic gap

Now, he says, the interest in peptides puts compounding pharmacies in an area where they start to act like mass drug producers. He says compounding pharmacies have been inspected and regulated by states more than the FDA, and in some cases there have been outcomes where theres been bacterial contamination and issues with quality control and dosing that would typically be caught in a larger manufacturing process but are missed. Our system works really well There isnt enough efficacy and safety data to approve these peptide injectables as traditional drugs, but Zuckerman says that the FDA is facing the reality that a lot of Americans are interested in drugs that they feel probably work and are probably safe

Owens MJ, Morgan WN, Plott SJ, Nemeroff CB

The conclusion is that B vitamins can be used in treating neuroinflammation and promoting neuroregeneration, potentially serving as an effective therapy for PNI in humans.