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doi: 10.3389/fphar.2021.643972 Received 19 December 2020 Accepted 26 January 2021 Published 13 April 2021 Volume 12 - 2021 Edited by Fatma Mohamady El-Demerdash, Alexandria University, Egypt Reviewed by Tanmoy Rana, West Bengal University of Animal and Fishery Sciences, India Zunzhen Zhang, Sichuan University, China Dr