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The bad news is if you dont have enough vitamin D to bind to those VDREs, serotonin synthesis plummets and some people really feel the domino effect of that drop in serotonin
This gap in knowledge hinders future clinical applications
However, TMD that persists beyond a few weeks, or that is associated with jaw clicking , bite changes, or recurring headaches, warrants a formal evaluation
It had been placed in a restricted compounding category and was removed from that restricted list in April 2026 as part of a procedural review reset but removal is not approval
