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At the molecular mechanism level, the core mediators of heart-liver interaction include: (1) Inflammatory signal cascade (Correale et al., 2018):Myocardial infarction induces inflammatory responses in the liver and leads to liver injury, while exercise-induced myogenic factor Irisin inhibits liver inflammatory responses and improves liver injury caused by myocardial infarction (Wang et al., 2023a)

Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice

2.3 Total phenolic and total flavonoid compounds of NSS, NSO Spectrophotometer, UV/Vis, Jenway, England, was used under environmental conditions: temperature of 20C and 37% rH humidity

Precautions Food supplements should not be used as a substitute for a balanced diet and a healthy lifestyle