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When they are impaired because of nutrient deficiencies, genetic variation, or other metabolic disturbances, homocysteine levels rise, making it a clinically useful marker of impaired one carbon metabolism

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Eweje F., Ibrahim V., Shajii A., et al., SelfAssembling Protein Nanoparticles for Cytosolic Delivery of Nucleic Acids and Proteins, Nature Biotechnology (2025): in press

Beyond the direct role of macrophage in fibrin clot removal, macrophage and other phagocytes have also been shown to modulate thrombosis through the removal of active coagulation factors and activated platelets thus decreasing the ability for thrombus formation [96]