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Although no clinical trials have yet evaluated this specific triplet, individual components and dual combinations have shown promising results in R/R AML models ( 4 Opportunities and challenges Although conventional chemotherapy has improved remission rates to some extent, relapse and drug resistance remain major obstacles to successful treatment

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Transcranial magnetic stimulation over the dorsolateral prefrontal cortex, responsible for cognitive control, has been shown to have effects on the excitatory modulation of cortical and deep brain areas through current pulses [136,137,138,139,140,141,142,143]

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