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These findings were supported by the relaxation of large vessels (ex vivo), mainly by acting on vascular endothelial cells but also on vascular smooth muscle cells, increasing NO production and migration of endothelial cells, activating the signal pathways of Src, Cav-1, and eNOS, and reducing proteinprotein interaction between eNOS and Cav-1 [121,122]

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Changes in mental status are thought to be caused by the liver failing to detoxify neurotoxic compounds like ammonia

Glutathione peroxidase activity was measured using the Glutathione Peroxidase Assay Kit provided by Cayman Chemical Company, USA