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Description
Indirect mechanisms have also been proposed, particularly in the context of androgen deficiency
They may support blood flow regulation through modulating vasodilation
All studies cited below are the work of their respective authors and institutions
Importantly, in our comparative analyses, phenformin strongly outcompeted metformin in terms of its antiviral activity which was ~300 fold higher against SARS-CoV-2 (IC 50 of ~1.5 M for phenformin vs ~450 M for metformin)
