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This is why some patients with normal haemoglobin levels may still experience significant fatigue and neurological symptoms when B12 deficient

doi: 10.3389/fphar.2022.839464 86 ChenJLiSGeYKangJLiaoJFDuJFet al

Although its use in ligand selection for large scale of affinity chromatography is not wide, ribosome display and systematic evolution of ligands by exponential enrichment (SELEX) may be mentioned as another approach and a potential ligand design and selection method due to its versatility and rapidity [9]

Elimination of VPA follows first-order kinetics, with a half-life ranging from 5 to 20 hours (mean 11 hours)