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doi: 10.1155/2019/5796491 148 MilajerdiAMousaviSMSadeghiASalari-MoghaddamAParohanMLarijaniBet al

The elevated levels of proinflammatory cytokines and chemokines such as tumour necrosis factor (TNF)-, interleukin 1 (IL-1), IL-6, IL-8 [2,7] and others indicate the cytokine storm plays a central role in the immunopathology of COVID-19, but the primary source or the exact virological mechanisms behind it have not been identified yet [8]

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It also notes that if the intestinal lining is still being irritated by ongoing triggers such as poor diet, stress, alcohol, or chronic drug exposure, symptoms may continue and progress may take longer