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Additionally, in vitro experiments showed that exosomal SELENOP potentially crossed the BBB and supplemented Se to neuronal cells (mouse neuroblastoma N2a cells), inducing the production of intracellular selenoproteins
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Metals, often with an oxidation number of + 2, such as Pb 2+ , Cd 2+ , and Hg 2+ are bound with chelating molecules by coordination bonds (Sears 2013)
Watari Y., Yamamoto Y., Brydun A., Ishida T., Mito S., Yoshizumi M., Igarashi K., Chayama K., Ohshima T., Ozono R., Hypertens Res 2008, 31, 783
