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Overall, the underlying pathophysiological mechanism of bone fragility in diabetes is very complex, including hyperglycemia, oxidative stress, and the accumulation of advanced glycosylation end products, which will damage the characteristics of collagen, increase bone marrow obesity, release inflammatory factors and adipokines from visceral fat, and may change the function of bone cells
A.Goutham KotaV.et al (2025)

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The business cycle is fundamentally about understanding the dynamics of these two objects
