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Simo A, Kawal N, Paliyath G, Bakovic M (2014) Botanical antioxidants for skin health in the world of cosmeceuticals

Not only because multiple (but rare) inherited defects have been found causing various forms of B 12 deficiency, as extensively reviewed by Froese DS et al
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One of the most actively pursued targets for small-molecule intervention is the indoleamine 2,3-dioxygenase 1 (IDO1) enzyme, which catalyzes tryptophan degradation and contributes to immune suppression within the tumor microenvironment (TME)
