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[3] Currently, a diagnosis of IPF requires: Exclusion of known causes of interstitial lung disease (ILD), e.g., domestic and occupational environmental exposures, connective tissue disorders, or drug exposure/toxicity The presence of a typical radiological pattern of usual interstitial pneumonia (UIP) on high-resolution computed tomography (HRCT)

Therefore, to overcome this, cholesterol is incorporated into the lipid bilayer which also provides additional improved stability to the liposome while circulating in the blood vessel [137, 140]

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