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Signaling pathways downstream of EGFR include ERK/MAPK, PI3K/AKT, and JAK/STAT
Additionally, D-NAC was shown to be more effective than NAC in bypassing the cysteineglutamate antiporter (Xc-) for cell uptake, increasing the GSH levels while preventing both glutamate release and excitotoxicity in mixed glia derived from Mecp2-null mice, a model of Rett syndrome
The ChEMBL25 data used in this study are available in the ChEMBL25 database here [ Source data are provided with this paper
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