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Statins reduce L-carnitine and acylcarnitine levels through HMG-CoA reductase inhibition, thereby decreasing mitochondrial acylcarnitine accumulation [174]
A study of 179 diagnosed women, aged 20-75 years, found that being overweight was significantly associated with increased pain severity, reduced physical mobility, and poorer quality of life overall (22)

doi: 10.3389/fmicb.2023.1237993 115

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