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Septic cardiomyopathy (SIC) In a model of LPS-mediated septic cardiomyopathy, some researchers revealed that LPS caused ferroptosis and septic cardiac injury by downregulating GPX4 protein levels and increasing COX-2 [93]

Both endonuclease G and AIF translocate to the nucleus and cause DNA fragmentation [53]

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These findings suggest SFN may support existing respiratory therapies rather than act as a standalone treatment
