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Description
Many perioperative factors can affect the gut microbiota, including the operation itself, antibiotics, opioids or acid-inducing drugs (Krezalek and Alverdy, 2016)

In Zermats case, the consultant requests focus on data integrity (still a topic of significant concern for FDA)

unknown long-term human safety profile Semaglutide : GI side effects common (nausea 44%, diarrhea, vomiting)
Those who have had bariatric surgery or other gastrointestinal procedures often have less stomach surface area available for vitamin absorption
