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Therapeutic and preventive potential of plant-derived antioxidant nutraceuticals

In addition, they found that let-7 bound directly 3UTR of IGF-1R as well as IRS-2 and insulin receptor (INSR) suggesting that let-7 may function as a regulator of glucose metabolism by targeting multiple components of growth/metabolic signaling pathway genes

Competitive but atoxigenic mold species and variants can supersede toxin-producing Aspergillus species and, hence, are suitable candidates in the elaboration of various biocontrol strategies (Kagot et al., 2019)

6.2 Cervical cancer Retrospective cohort studies demonstrated that metformin use in patients with diagnosed T2DM was associated with a lower risk of cervical cancer (Takiuchi et al., 2017), several studies revealed that metformin treatment decreased cervical cancer-specific and overall mortality in older women with T2DM ( It has been reported that metformin inhibits cell viability, migration, and metastasis and induces cell-cycle arrest, autophagy, and apoptosis in cervical cancer cell lines and cervical cancer xenografts (Xia et al., 2018)