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doi: 10.3324/haematol.2017.171074 [DOI] [PMC free article] [PubMed] [Google Scholar] 75
Immune cells, particularly lymphocytes and macrophages, undergo distinct metabolic reprogramming upon activation to meet the demands of proliferation, cytokine production, and effector functions 13
By months four through six, the medication has generally reached its target dose and patients are experiencing its full metabolic effect
Nintedanib is a potent receptor tyrosine kinase inhibitor that targets multiple signaling pathways implicated in IPF
