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Discussion We found that IGF-1 had poor accuracy as demonstrated by low AUC, and poor sensitivity, specificity, and DE for the best cutoff of 1.493 SD

This really comes down to safety and effectiveness

Acknowledgements Research reported in this publication included work performed in the Integrative Genomics Core and the Integrated Mass Spectrometry Shared Resource supported by the National Cancer Institute of the National Institutes of Health under grant number P30CA033572
