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The dry and wet forms of beriberi involve peripheral neuropathy, whereas cerebral beriberi can lead to neuronal cell death and the clinical conditions of Wernicke's encephalopathy and Korsakoff's psychosis, especially in those who chronically abuse alcohol (22, 24)

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et al, Hyperhomocysteinemia and low pyridoxal phosphate: common and independent reversible risk factors for coronary artery disease

It could manifest as dark spots, inconsistent skin tones, or blotchy patches