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After pulling out all five sheets randomly, all sheets were returned to the drawer and this procedure was continued for the next five patients until the desired sample size was reached

Following the breakthrough discovery that small RNA-based pathways emerge as regulatory mechanisms for post-transcriptional control of gene expression in multicellular eukaryotes 19,20 , these RNA species have gained significant attention

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Upon crossover, those initially on C10-enriched KD maintained their seizure reduction, while patients initially on the classic KD showed additional seizure reduction when switched to C10-enriched KD