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Cysteine is often the limiting factor, which is why compounds like N-acetylcysteine (NAC) are so heavily researched for their ability to boost glutathione levels

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The combination of AOD9604 with HA was more effective than either treatment alone, suggesting a synergistic interaction

FIGURE 2 2 Search strategy and selection criteria In order to comprehensively review the pharmacological effects of PNS and its therapeutic potential for cerebrovascular neurological disorders, we systematically searched multiple Chinese and English databases (including Web of Science, PubMed, Embase, and CNKI), with a time frame from the inception of each database to 31 May 2025, and supplemented the references of relevant literature through manual searches