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They are among the most clinically studied peptides in modern medicine

Blood tests help confirm deficiency, monitor the effectiveness of injections, and prevent unnecessary overuse

Given the electrophilicity of EA and the nucleophilicity of the active site of FXIIIa, we hypothesized that EA may inhibit FXIIIa affecting the clotting process in a way that potentially, and at least partially, explains the bleeding consequences of using intravenous EA

Regarding its multi-functionality as a nutrient, protein folding, and major component for redox balance due to its involvement in glutathione synthesis, disruption of cysteine homeostasis appears to be promising strategy for induction of cancer cell death