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To clarify by an example, some miRNAs, including miR-221, miR-222, miR-140, miR-21, and miR-22, have carcinogenic effects, while the inverse is true for other miRNAs considered immensely potent to suppress tumor cells, namely miR-200 family, miR-128, miR-99a, miR-29b, Let-7 miRNA, miR-600, miR-34, and miR-30

It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone

How do neuroendocrine and inflammatory pathways interact during stress to contribute to the pathogenesis of depression