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Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme a desaturase 1 expression

When your target is 25 units (2.5 mg at 10 mg/mL), reading the 25th line on a 0.5 mL syringe is much easier and more accurate than trying to hit the midpoint between 24 and 26 on a 1 mL syringe where lines are spaced closer together

Using RNA interference strategies Blanger and collaborators observed that a similar decrease in Glo-1 activity (80%) does not impact astrocytic and neuronal cell viability to the same extent using primary mouse cortical cultures as a model (Blanger et al., 2006b)