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The E3 ubiquitin ligase Trim63 (also known as MuRF1) can regulate the activity of key enzymes involved in fatty acid oxidation (FAO), such as CPT1A and ACOX1, by affecting the activity of peroxisome proliferator-activated receptor (PPAR)
The rhythms observed in control flies were not evident in the clock mutants, thus linking glutathione production and utilization to the circadian system
Moriya, J
This is consistent with the observation that capsid proteins obtained from BSO-treated cells can still associate with RNA to form 150S, albeit unable to produce mature virion
