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Another meta-analysis further confirmed the lack of overall association of MTHFR C667T polymorphism with PD

Mechanistically, AZM activates the sphingomyelin (SM) metabolic pathway, leading to reduced goblet cell proliferation and inhibition of Th2 cytokines, including IL-5 and IL-13, thereby attenuating type 2 airway inflammation (Huang et al., 2025)

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