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Description
found methylation in the hMLH1 promoter region in peripheral blood lymphocytes in 4 of 30 patients with juvenile-onset sporadic colon cancer or multiple cancer, and one of the four patients had multiple cancer, including endometrial cancer [34]
As a single-center retrospective analysis, it may be subject to selection bias, and conclusions should be validated in large-scale multicenter prospective studies
10.1097/tp.0000000000001999 50 KarahanM
doi: 10.3748/wjg.v16.i12.1436
