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Do not rub or massage the area

In 1994, a combination of dimethylfumarate and three salts of monoethylfumarate, Fumaderm, was approved in Germany for the treatment of psoriasis (Dunn 2013)

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Esto se realiza en primera instancia obteniendo cistationina (un intermediario de la cistena), mediante la CBS (Cistationina Beta Sintasa), que usa el factor pirixodal de la vitamina B6 como cofactor, formando cistationina, a partir de la Homocistena y de la Serina (un aminocido que participa en la sntesis de purinas y a su vez es precursor de la glicina)