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Consequently, neoantigen immunoediting may drive anti-PD therapy efficacy [3, 101], and the tumor mutational burden has been shown to have predictive potential for identifying responders and nonresponders prior to or during treatment [103, 104]
In addition, Hou et al
In addition, the ER houses the sterol regulatory element-binding protein (SREBP) sensory machinery, which senses ER sterol levels and subsequently regulates transcription of genes involved in cholesterol and fatty acid synthesis and uptake (148)
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