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PubMed CrossRef Rosenberg R, Thorpy MJ, Doghramji K, et al

Healthy skeletal muscles are abundantly supplied with capillaries

If levels don't respond to standard supplementation, investigate possible MTHFR polymorphisms, malabsorption conditions like celiac or Crohn's disease, or potential medication interactions
Am J Clin Nutr 2000 Aug;72(2 Suppl):618S-23S Volek JS, Kraemer WJ, Rubin MR, Gomez AL, Ratamess NA, Gaynor P
