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[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Seitz H K, Simanowski U A, Garzon F T et al

Cardiovascular Disease When B12 levels are depleted, there is a tendency for homocysteine, which is correlated with heart disease, to rise

However, the Drugs and Lactation Database (LactMed), a definitive resource on such matters, states that milk thistle is "unlikely to adversely affect the breastfed infant" and that it's "generally well tolerated in adults with only mild side effects.21 Of course, no supplement is without its risks, so if you're considering milk thistle as a lactation aid, we recommend speaking with your doctor to confirm its suitability for you and your baby

This is probably due to the less efficient production of H 2 S n from H 2 S compared to that from 3MP