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PMC 4042564

While B-12 is found naturally in a balanced diet, deficiencies are common due to factors such as certain medications, poor digestion, stress, chronic illness, suboptimal eating habits, or the natural aging process

The standard NHS regimen for treating deficiency involves loading doses followed by maintenance therapy, with frequency determined by the underlying cause and severity of deficiency

This innovative approach has been shown to enhance the absorption and subsequent bioavailability of a variety of supplemental nutrients, such as vitamin D3, iron, and magnesium, suggesting that it could similarly improve the efficacy of oral B12 supplementation (2529)