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The result is skin that appears brighter and more uniform not because of surface-level bleaching, but because the underlying biochemistry has shifted

Many patients live with persistent fatigue, weakness, and reduced stamina for years without a clear explanation

[DOI] [PubMed] [Google Scholar] 34.Kawano T, et al

By contrast, the ACP does not provide a clear recommendation for urate-lowering therapy (ULT) for patients with frequent, recurrent flares or those with tophi, nor does it recommend monitoring serum urate levels of patients prescribed ULT