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24 In consequence, the risk of adverse effects associated with high blood levels, including the risk of hangover, would be lower
In mice with deficient peroxisomes in astrocytes and neurons, no axonal degeneration has been detected [43], however, a selective peroxisomal deficiency in oligodendrocytes leads to early axonal loss and neuroinflammation with no demyelination [44] suggesting that oligodendrocyte-axonal and myelin-axonal integrity is important in AMN
The major active metabolite is 9-hydroxyrisperidone (paliperidone)
